Breeder and Distributor of World’s Smallest-Class Laboratory Minipig.

Customers

  • Keio University
  • Kyoto University
  • Jichi Medical University
  • National Center for Child Health and Development(Japan)
  • Toho University
  • Gifu University
  • Tohoku University
  • Kyushu University
  • Kagoshima University
  • Hamri Co., Ltd.
  • Japan SLC, Inc.

and more

Collaborating Organizations

  • Marubeni Nisshin Feed Co., Ltd.
  • Joint Research with Swine & Poultry Research Center,
    Shizuoka Prefectural Research Institute of Animal Industry

and more

Related Publications

Japanese Publications

  • A Case of Beagle Dog Showing Hemorrhagic Death Due to External Iliac Arteriorrhexis Induced by Cathether Introducer
    Ando K, Nakamura Y, Cao X, Watanabe Y, Ohara H, Izumi-Nakaseko H, Sugiyama A.[Advances in Animal Cardiology 47 (1):7-11, 2014 DOI:10.11276/jsvc.47.7]
  • Hypothermia-Induced J Waves Observed in Microminipig
    Ando K, Ohara H, Nakamura Y, Cao X, Izumi-Nakaseko H, Sugiyama A.[Advances in Animal Cardiology 48 (1):9-13, 2015 DOI:10.11276/jsvc.48.9]

English Publications

  • “Pharmacological characterization of microminipig as a model to assess the drug-induced cardiovascular responses for non-clinical toxicity and/or safety pharmacology studies”
    Yokoyama H, Nakamura Y, Saito H, Nagayama Y, Hoshiai K, Wada T, Izumi-Nakaseko H, Ando K, Akie Y, Sugiyama A. [J Toxicol Sci. 2017;42:93-101. DOI:10.2131/jts.42.93]
  • “Characterization of microminipigs as an in vivo experimental model for cardiac safety pharmacology”
    Matsukura S, Nakamura Y, Cao X, Wada T, Izumi-Nakaseko H, Ando K, Yamazaki H, Sugiyama A. [J Pharmacol Sci.2017;133:103-109. DOI:10.1016/j.jphs.2017.02.002]
  • “Sensitivity and reliability of halothane-anaesthetized microminipigs to assess risk for drug-induced long QT syndrome”
    Cao X, Wada T, Nakamura Y, Matsukura S, Izumi-Nakaseko H, Ando K, Naito AT, Sugiyama A. [Basic Clin Pharmacol Toxicol. 2017;121:465-470. DOI:10.1111/bcpt.12838]
  • “Electropharmacological characterization of microminipigs as a laboratory animal using anti-influenza virus drug oseltamivir”
    Lubna NJ, Nakamura Y, Hagiwara-Nagasawa M, Goto A, Chiba K, Kitta K, Izumi-Nakaseko H, Ando K, Naito AT, Akie Y, Sugiyama A. [J Toxicol Sci. 2018;43:507-512. DOI:10.2131/jts.43.507]
  • “Use of microminipigs for unveiling unknown mechanisms of azithromycin-induced cardiovascular death”
    Goto A, Hagiwara-Nagasawa M, Izumi-Nakaseko H, Kitta K, Hoshiai K, Chiba K, Ando K, Akie Y, Naito AT, Sugiyama A. [J Pharmacol Sci. 2018; in press]
  • “Measurement of J-Tpeakc along with QT-interval prolongation may increase the assay sensitivity and specificity for predicting the onset of drug-induced torsade de pointes: Experimental evidences based on proarrhythmia model animals”
    Goto A, Hagiwara-Nagasawa M, Kambayashi R, Chiba K, Izumi-Nakaseko H, Naito AT, Kanda Y, Sugiyama A. [Cardiovasc Toxicol. in press, 2019]
  • “Characterization of microminipig as a laboratory animal for safety pharmacology study by analyzing fluvoxamine-induced cardiovascular and dermatological adverse reactions”
    Tanikawa Y, Hagiwara-Nagasawa M, Kambayashi R, Goto A, Chiba K, Kitta K, Hoshiai K, Izumi-Nakaseko H, Naito AT, Sugiyama A. [Cardiovasc Toxicol. in press, 2019]
  • “Coronary artery vasospasms in a microminipig occurred after placing an ameroid constrictor”
    Cao X, Nakamura Y, Aoki T, Wada T, Izumi-Nakaseko H, Ando K, Sakata R, Sugiyama A. [J Vet Med Sci. 2016;78:1213-1216. DOI:10.1292/jvms.16-0005]
  • “Feasible induction of coronary artery vasospasm occurred during cardiac catheterization in a microminipig.”
    Matsukura S, Nakamura Y, Ohara H, Cao X, Wada T, Izumi-Nakaseko H, Ando K, Akasaka Y, Sugiyama A. [J Vet Med Sci. 2016;78:873・76. DOI:10.1292/jvms.15-0426]4
  • “Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs”
    Ando K, Takahara A, Nakamura Y, Wada T, Chiba K, Goto A, Lubna NJ, Hagiwara-Nagasawa M, Izumi-Nakaseko H, Hoshiai K, Akie Y, Naito AT, Sugiyama A. [J Pharmacol Sci. 2018;136:86-92. DOI:10.1016/j.jphs.2018.01.002]
  • “Microminipig, a non-rodent experimental animal optimized for life science research”
    Kaneko N, Itoh K, Sugiyama A, Izumi Y. [Preface. J Pharmacol Sci. 2011;115:112-114]
  • “Microminipig, a non-rodent experimental animal optimized for life science research. In vivo proarrhythmia models of drug-induced long QT syndrome: development of chronic atrioventricular block model of microminipig”
    Sugiyama A, Nakamura Y, Akie Y, Saito H, Izumi Y, Yamazaki H, Kaneko N, Itoh K. [J Pharmacol Sci. 2011;115:122-126]
  • “Efficacy of precordial percussion pacing assessed in a cardiac standstill microminipig model”
    Wada T, Ohara H, Nakamura Y, Cao X, Izumi-Nakaseko H, Ando K, Honda M, Yoshihara K, Nakazato Y, Lurie KG, Sugiyama A. [Circulation J. 2017;81:1137-1143. doi.org/10.1253/circj.CJ-16-1106]
  • “Knocking the chest as a "bridge to pacemaker" -Reply-”
    Wada T, Hagiwara-Nagasawa M, Yoshihara K, Nakazato Y, Lurie KG, Sugiyama A. [Circ J. 2018;82:2446-2447. DOI:10.1253/circj.CJ-18-0765]